Detalhe da pesquisa
1.
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell
; 184(18): 4784-4818.e17, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450027
2.
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell
; 184(24): 6003-6005, 2021 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822786
3.
An epigenome-wide view of osteoarthritis in primary tissues.
Am J Hum Genet
; 109(7): 1255-1271, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35679866
4.
A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis.
Hum Mol Genet
; 31(12): 2090-2105, 2022 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35088088
5.
Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis.
Ann Rheum Dis
; 82(7): 963-973, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927643
6.
Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis.
Rheumatology (Oxford)
; 62(4): 1669-1676, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040165
7.
Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants.
Rheumatology (Oxford)
; 62(2): 894-904, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35532170
8.
The role of TNFRSF11B in development of osteoarthritic cartilage.
Rheumatology (Oxford)
; 61(2): 856-864, 2022 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33989379
9.
Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis.
Rheumatology (Oxford)
; 61(7): 3023-3032, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730803
10.
Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes.
Rheumatology (Oxford)
; 62(1): 457-466, 2022 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35383365
11.
Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.
Ann Rheum Dis
; 80(3): 367-375, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33055079
12.
Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration.
Rheumatology (Oxford)
; 60(3): 1166-1175, 2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32885253
13.
The miRNA-mRNA interactome of murine induced pluripotent stem cell-derived chondrocytes in response to inflammatory cytokines.
FASEB J
; 34(9): 11546-11561, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32767602
14.
A Combined mRNA- and miRNA-Sequencing Approach Reveals miRNAs as Potential Regulators of the Small Intestinal Transcriptome in Celiac Disease.
Int J Mol Sci
; 22(21)2021 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34768815
15.
RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.
Ann Rheum Dis
; 78(2): 270-277, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30504444
16.
Identified senescence endotypes in aged cartilage are reflected in the blood metabolome.
Geroscience
; 46(2): 2359-2369, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37962736
17.
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.
Nat Commun
; 15(1): 888, 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38291025
18.
Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility-Towards Identification of Applicable Early OA Biomarkers.
Biomolecules
; 11(9)2021 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34572569
19.
Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants.
Arthritis Res Ther
; 23(1): 215, 2021 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34399844
20.
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.
Arthritis Rheumatol
; 73(5): 789-799, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33258547